Recombinant CLDN18.2 (Zolbetuximab Biosimilar) 抗体
This anti-CLDN18.2 (Zolbetuximab Biosimilar) antibody is a Humanized 单克隆 antibody detecting CLDN18.2 (Zolbetuximab Biosimilar) in FACS 和 in vivo. Suitable for 人.
Quick Overview for Recombinant CLDN18.2 (Zolbetuximab Biosimilar) 抗体 (ABIN7795131)
抗原
CLDN18.2 (Zolbetuximab Biosimilar)
抗体类型
Recombinant Antibody
适用
人
宿主
Humanized
克隆类型
单克隆
标记
This CLDN18.2 (Zolbetuximab Biosimilar) antibody is un-conjugated
应用范围
Flow Cytometry (FACS), In vivo Studies (in vivo)
质量等级
Research Grade
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Expression System
- Mammalian cells
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原理
- Zolbetuximab Biosimilar, Claudin 18.2 Monoclonal Antibody
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产品特性
- What is zolbetuximab biosimilar research grade? Zolbetuximab is a humanized monoclonal antibody directed against the human protein Claudin 18.2 (the isoform 2 of Claudin), and potentially used for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. Zolbetuximab is an Fc-engineered, humanized, monoclonal antibody (IgG1κ isotype). Zolbetuximab biosimilar uses the same protein sequences as the potential therapeutic antibody zolbetuximab . Claudin-18 in humans is a protein encoded by the CLDN18 gene. The CLDN18 protein belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human Claudin 18.2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CLDN18.2 (Zolbetuximab Biosimilar)
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别名
- Zolbetuximab Biosimilar
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物质类
- Biosimilar
抗原
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